New research indicates that patients with Multiple Sclerosis (MS) can regulate T cell hyperactive immune system response with high doses of Vitamin D3 (cholecalciferol). MS is a central nervous system disease that disrupts information within the brain, which can affect signals sent to other parts of the body that can cause psychical debilities like paralysis. Prior to this study, researchers found a direct link to the development and progression of MS to deficiencies of Vitamin D.
Vitamin D3 and Multiple Sclerosis
The research study published by the Journal of the American Academy of Neurology focused on patients with relapsing-remitting MS that had low levels of blood Vitamin D. Patients with severe Vitamin D deficiency however, were excluded from the study.
During the research trial, one group of participants with MS were given 10,400 IU of Vitamin D3, while the second group was given 800 IU of Vitamin D3 over a six month period. To monitor the effects of Vitamin D3 on T cells, patients were administered blood tests at the beginning of the clinical trial, and then three and four months into the trial period. T cells L-17+CD4+ and CD161+CD4+ are noted by researchers to cause severe cases of MS, which result in problems with vision, balance, muscle control, and simple body functions.
The results of the study found that the first group of patients taking 10,400 IU of Vitamin D3 had a significant decrease in inflammatory T cells, which are directly linked to the severity of MS. While the second group, which was given 800 IU of Vitamin D3, had no significant change in T cells. Specifically, researchers found that the patients that were given the high dose of 10,400 IU of Vitamin D3 had a 1% reduction in T cells L-17+CD4+ T.
Given that this degenerative disease often requires multiple specialists to treat and manage, the significance of this finding could offer the development of low-cost treatment options for patients with relapsing-remitting multiple sclerosis. This trial in particular paves the way for future research for determining how the reduction inflammatory T cells L-17+CD4+ and CD161+CD4+ can reduce the severity in some various types of MS.
Calcitriol Prescription Vitamin D
Vitamin D is also known as cholecalciferol, and like many vitamins, it is converted into different forms by the body in order for it to be useful. The final form of a vitamin that the body can utilize is known as an active metabolite. Calcitriol is the active metabolite of vitamin D. As a vitamin D supplement, your doctor may prescribe vitamin D3, cholecalciferol or calcitriol. HelpRx provides discounts on all the above. Search our site for discounts on these and other MS medications.
